Optical Coherence Tomography

Optical coherence tomography (OCT) prior to peroral endoscopic myotomy (POEM) reduces procedural time and bleeding: a multicenter international collaborative study.

Desai, AP; Tyberg, A; Kedia, P; Smith, MS; Martinez, G; Zamarripa, F; Schneider, Y; Bertani, H; Frazzoni, M; Casas, F; Khanna, LG; Lambroza, A; Kumta, NA; Khan, A; Sharaiha, RZ; Salgado, S; Gaidhane, M; Sethi, A; Kahaleh, M

BACKGROUND: Per-oral endoscopic myotomy (POEM) has emerged as an endoscopic treatment of achalasia. There are no pre-procedural imaging modalities to predict the safest and the most efficacious approach. AIM: To evaluate the use of optimal coherence tomography (OCT) in providing a pre-procedural esophageal assessment. METHODS: Patients undergoing POEM from July 2013 to November 2015 were captured in a multicenter, international registry. Patients who underwent OCT pre-POEM ("OCT arm") were compared to patients without pre-POEM OCT ("control arm"). OCT images were assessed for the degree of vascularity and the thickness of the circular muscular layer, and an approach was determined. RESULTS: A total of 84 patients were captured in the registry. Fifty-one patients underwent pre-POEM OCT. Using OCT as a guide, 24 (47 %) of patients underwent anterior POEM while 27 (53 %) underwent posterior POEM. Technical success was achieved in 96 % of patients. Significantly less bleeding occurred in the OCT arm when compared to the control group [4 (8 %) vs. 14 (43 %), p = 0.0001]. As a result, procedural time was significantly lower in the OCT group as compared to the control group (85.8 vs. 121.7 min, p = 0.000097). CONCLUSION: Pre-POEM OCT results in a reduction in procedural bleeding which contributes to a reduction in overall procedural time. CLINICAL TRIAL REGISTRATION: NCT01438385.

PMID: 27059973 URL  - http://www.ncbi.nlm.nih.gov/pubmed/27059973?dopt%3DCitation&;source=gmail&ust=1476417929599000&usg=AFQjCNHkrEnrMkVQOCm80EM-pj9geVTOBw" style="color:rgb(17, 85, 204)" http://www.ncbi.nlm.nih.gov/pubmed/27059973?dopt=Citation

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